The potential of polymeric film-forming systems as sustained delivery platforms for topical drugs

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Formulation considerations in the design of topical, polymeric film-forming systems for sustained drug delivery to the skin.

Polymeric film-forming systems (FFSs) are potential drug delivery systems for topical application to the skin. The FFSs form thin and transparent polymeric films in situ upon solvent evaporation. Their application convenience and cosmetic attributes, superior to conventional semi-solids, may offer improved patient compliance. This study represents the first phase of an investigation into the us...

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With the emergence of novel and more effective drug therapies, increased importance is being placed upon the drug delivery technology. Topical formulations are attractive alternatives to oral formulations and offer several advantages, such as avoiding first-pass hepatic metabolism and gastric degradation. The major obstacle to drug delivery across the skin (transdermal) is the barrier nature of...

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ژورنال

عنوان ژورنال: Expert Opinion on Drug Delivery

سال: 2015

ISSN: 1742-5247,1744-7593

DOI: 10.1517/17425247.2016.1124412